The Independent Socioenvironmental Rio Sonora Water Project (PSIRS in Spanish) was catalyzed by the 2014 12-million-gallon acid spill from Grupo Mexico’s Cananea Mine that devastated the Rio Sonora and neighboring communities for 200 miles to the south. PSIRS devises strategies to protect the water, health, environment, and livelihood of communities along the river by joining scientific and social science experts and activists, the majority of which are Sonoran volunteers.